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--- research:woo_jun_shim [2018/03/24 13:26] – chris
+++ research:woo_jun_shim [2019/05/03 10:24] (current) – chris
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 **Woo Jun (Chris) Shim**
-Woo Jun is currently pursuing PhD under supervision of Assoc. Prof. Mikael Boden and Dr. Nathan Palpant. His current research work centres around epigenetic regulation of genes that drive cell fate, which can be summarised in a threefold approach.
+E-mail: woo.shim@uqconnect.edu.au \\
+LinkedIn: [[https://www.linkedin.com/in/woo-jun-shim-375276132/ | Woo Jun Shim]] \\
+Twitter: [[https://twitter.com/woojunshim3/ | Woo Jun Shim]] \\
+Woo Jun is currently pursuing PhD under supervision of Assoc. Prof. Mikael Boden (SCMB, UQ) and Dr. Nathan Palpant (IMB, UQ). His current research work centres around epigenetic regulation of genes that drive cell fate, which can be summarised in a threefold approach.
 * Identifying key epigenetic features associated with regulation of cell identity genes.
@@ Line 7: / Line 12: @@
 * Understanding epigenetic gene regulation by integrating those epigenetic features.
-* Devising computational methods to provide insights into regulatory roles of genes.
+* Devising computational methods to infer genetic regulators of cell identity.
-Leveraging abundance of public datasets (e.g. from ROADMAP and ENCODE projects), Woo Jun studies histone modifications, open chromatin structures and non-coding RNAs across various cell contexts. Main question is how dynamics of these epigenetic features are functionally linked to expression of cell identity genes that drive an intended cell fate. If we can extract a set of "epigenetic roles" that governs cell identity, these would provide a useful reference to build a computational model to infer regulatory importance of genes.
+Leveraging abundance of public datasets (e.g. from ROADMAP and ENCODE projects), Woo Jun studies histone modifications, open chromatin structures and non-coding RNAs across various cell contexts. Main question is how dynamics of these epigenetic features are functionally linked to expression of cell identity genes that drive an intended cell fate. If we can extract a set of epigenetic "rules" that governs cell identity, these would provide a useful reference to build a computational model to infer genetic regulators of cell identity.
-Woo Jun has Master of Bioinformatics (UQ, 2016) and Bachelor degrees in Pharmacy (UQ, 2008) and Biomedical science (Adelaide, 2004). He is a registered pharmacist and worked in Australia for 7 years before coming back to Uni. With knowledge and experience in pharmacy and biology, Woo Jun is interested in applying bioinformatics methods to tackle broad biological and clinical questions (e.g. developmental biology, cancer pathology, personalised medicines).
+Woo Jun has Master of Bioinformatics (UQ, 2016) and Bachelor degrees in Pharmacy (UQ, 2008) and Biomedical science (Adelaide, 2004). He is a registered pharmacist and worked in Australia for 7 years before coming back to Uni. He worked extensively in the community pharmacy and performed more than 150 home medicines reviews (HMRs) as an accredited consultant pharmacist. With knowledge and experience in pharmacy and biology, Woo Jun is interested in applying bioinformatics methods to tackle broad biological and clinical problems (e.g. developmental biology, cancer pathology, personalised medicines).
-**Publications**
+** Publications **
-Cell identity genes are frequently and distinctively associated with broad H3K27me3 domains across cell types. 2018. (manuscript in preparation).
+Shim, WJ., Piper, M., Palpant, N., Boden, M. (2018) Cell identity genes are predicted by the absence of broad H3K27me3 domains. //Bioinformatics// (in revision)
+Shim, WJ., Sinniah, E., Xu, J., Vitrinel, B., Alexanian, A., Andreoletti, G., et al. (2019) Comparative analysis of diverse cell states establishes an epigenetic basis for inferring regulatory genes governing cell identity. (manuscript in preparation)
-**Conferences**
+**Conference talk**
+Cell identity genes are predicted by the absence of broad H3K27me3 domains. ABACBS National Conference, Melbourne, 2018.
+**Conference poster**
 Sortilin localisation in the rat retina during early postnatal  development. 29th Annual Meeting Australian Neuroscience Society, Canberra, Australia, Jan. 2009. Poster.
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 **Awards**
+ABACBS Conference Travel Award.
 SCMB Master of molecular biology and master of bioinformatics prize 2016 (UQ, SCMB), awarded to the graduating student with the highest GPA of their class.