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evolusec [2018/09/21 14:50] – [Supplementary Data] sean | evolusec [2020/04/11 15:38] – [Application] sean |
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class=SpellE><span lang=EN-GB>Evolu</span></span><span lang=EN-GB>-sec package | class=SpellE><span lang=EN-GB>Evolu</span></span><span lang=EN-GB>-sec package |
forms part of a research project, reported in “Modelling the evolution of protein secondary | forms part of a research project, reported in “Evolutionary model of protein secondary structure capable of revealing new biological relationships”.<o:p></o:p><a href="http://dx.doi.org/10.1101/563452">http://dx.doi.org/10.1101/563452</a></span></p> |
structure: a new phylogenetic metric suitable for assessing structural | |
similarity”.<o:p></o:p></span></p> | |
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class=SpellE><span lang=EN-GB>Evolu</span></span><span lang=EN-GB>-sec package | class=SpellE><span lang=EN-GB>Evolu</span></span><span lang=EN-GB>-sec package |
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The research project abstract is provided in the next section. The dataset for the model development and the software can be accessed in the [[http://bioinf.scmb.uq.edu.au/evolusec#supplementary_data|“Supplementary Data”]] section. | The research project abstract is provided in the next section. The dataset (140.9MB) for the model development and the software can be accessed in the [[http://bioinf.scmb.uq.edu.au/evolusec#supplementary_data|“Supplementary Data”]] section. |
{{:research:evolusec.png}} | {{:research:evolusec.png}} |
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==== Research Project ==== | ==== Research Project ==== |
**Modelling the evolution of protein secondary structure: a new phylogenetic metric suitable for assessing structural similarity**\\ | **Evolutionary model of protein secondary structure capable of revealing new biological relationships**\\ |
[[http://bioinf.scmb.uq.edu.au/research/jhih_siang_sean_lai|Jhih-Siang Lai]], [[https://www.rostlab.org/|Burkhard Rost | [[http://bioinf.scmb.uq.edu.au/research/jhih_siang_sean_lai|Jhih-Siang Lai]], [[https://www.rostlab.org/|Burkhard Rost |
]], [[http://kobelab.biosci.uq.edu.au/wiki/|Bostjan Kobe]] and [[http://bioinf.scmb.uq.edu.au/research/mikael_boden|Mikael Bodén]]\\ | ]], [[http://kobelab.biosci.uq.edu.au/wiki/|Bostjan Kobe]] and [[http://bioinf.scmb.uq.edu.au/research/mikael_boden|Mikael Bodén]]\\ |
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==== Supplementary Data ==== | ==== Supplementary Data ==== |
Supplementary data for "**Modelling the evolution of protein secondary structure: a new phylogenetic metric suitable for assessing structural similarity**" can be downloaded from\\ [[https://cloudstor.aarnet.edu.au/plus/s/r9Sml5YC6jx6Wfn|Dataset]] or [[https://cloudstor.aarnet.edu.au/plus/s/Sp17tsX26sgOmlb|Software]], separately.\\ | Supplementary data for "**Evolutionary model of protein secondary structure capable of revealing new biological relationships**" can be downloaded from\\ [[https://cloudstor.aarnet.edu.au/plus/s/r9Sml5YC6jx6Wfn|Dataset (140.3 MB)]] or [[https://cloudstor.aarnet.edu.au/plus/s/Sp17tsX26sgOmlb|Software (617 KB)]], separately.\\ |
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Package may be downloaded as a single archive from\\ [[https://cloudstor.aarnet.edu.au/plus/s/IR7C4llrOhutlcs|Full package download]].\\ | Package may be downloaded as a single archive from\\ [[https://cloudstor.aarnet.edu.au/plus/s/IR7C4llrOhutlcs|Full package download (140.9 MB)]].\\ |
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* (Ancestral secondary structure reconstruction) ASSR needs version MATLAB 8.2 (R2013b) or later.\\ | * (Ancestral secondary structure reconstruction) ASSR needs version MATLAB 8.2 (R2013b) or later.\\ |
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| ==== Application ==== |
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| <p class=MsoNormal><a name="_GoBack"></a>NAD<sup>+</sup> cleavage activity by |
| animal and plant TIR domains in cell death pathways, <i>Science</i>, 365, 6455, |
| 2019.</p> |
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| href="http://www.doi.org/10.1126/science.aax1911">http://www.doi.org/10.1126/science.aax1911</a></span></p> |
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==== External links ==== | ==== External links ==== |
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[[https://www.researchgate.net/profile/Jhih_Siang_Lai|Sean in ResearchGate]]\\ | [[https://www.researchgate.net/profile/Jhih_Siang_Lai|Sean in ResearchGate]]\\ |
[[research:jhih_siang_sean_lai|Sean's profile]]\\ | [[research:jhih_siang_sean_lai|Sean's profile]]\\ |
| [[https://orcid.org/0000-0001-5677-5890|Sean in ORCID]]\\ |
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