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open_projects [2026/08/07 09:57] – remove Michael Hall's project projectopen_projects [2026/08/07 09:58] (current) – update Michael Hall email project
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 === Pangenomes to predict bacterial transmission in healthcare settings === === Pangenomes to predict bacterial transmission in healthcare settings ===
  
-Contacts: Leah Roberts l.roberts3@uq.edu.au, Michael Hall michael.hall2@unimelb.edu.au+Contacts: Leah Roberts l.roberts3@uq.edu.au, Michael Hall michael.hall1@uq.edu.au
  
 Predicting whether two bacterial isolates are the same (and thereby inferring if transmission has occurred) has traditionally been performed by identifying and counting single nucleotide variants (SNVs). To do this, a reference genome is usually selected, and isolate reads are mapped to the reference to identify SNVs in regions shared between all isolates. However, for large datasets of very diverse bacterial strains, a single reference genome is usually insufficient, as the shared regions between the strains becomes a very small proportion of the total genomic content. Predicting whether two bacterial isolates are the same (and thereby inferring if transmission has occurred) has traditionally been performed by identifying and counting single nucleotide variants (SNVs). To do this, a reference genome is usually selected, and isolate reads are mapped to the reference to identify SNVs in regions shared between all isolates. However, for large datasets of very diverse bacterial strains, a single reference genome is usually insufficient, as the shared regions between the strains becomes a very small proportion of the total genomic content.
open_projects.txt · Last modified: 2026/08/07 09:58 by project